country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

製品番号: HY-134199

Copy Link Print Information

IMP-1002

IMP-1002 is a Plasmodium N-myristoyltransferase (NMT) inhibitor. IMP-1002 inhibits myristoylation activity, blocks parasite development. IMP-1002 can be used for the research of malaria.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 2059148-58-0
分子式: C₂₅H₃₀FN₅O
分子量:435.55

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

IMP-1002 構造式

CAS 番号: 2059148-58-0

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

IMP-1002 is a Plasmodium N-myristoyltransferase (NMT) inhibitor. IMP-1002 inhibits myristoylation activity, blocks parasite development. IMP-1002 can be used for the research of malaria^[1].

Parasite アイソフォーム固有の製品をすべて表示 :

体外実験

IMP-1002 (0.54-400 nM; 96 h) potently inhibits the growth of P. falciparum 3D7 erythrocytic stage parasites with an EC₅₀ of 34 ± 5.8 nM following 96 h of treatment^[1].
IMP-1002 (140 nM) inhibits protein myristoylation in P. falciparum 3D7 WT parasites during the 36-45 h post-invasion window, but does not inhibit myristoylation in PfNMT^[G386E] clones^[1].
IMP-1002 (140 nM; 45 h) induces developmental arrest in P. falciparum 3D7 WT parasites during a 45 h post-invasion treatment period, but does not arrest development in PfNMT^[G386E] clones^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 2059148-58-0
分子量 435.55
分子式 C₂₅H₃₀FN₅O
SMILES

FC=1C=CC(=C(OCCC=2C(=NN(C2C)C)C)C1)C3=CC=C4C(=C3)C(=NN4C)CN(C)C
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Schlott AC, et al. Structure-Guided Identification of Resistance Breaking Antimalarial N‑Myristoyltransferase Inhibitors. Cell Chem Biol. 2019;26(7):991-1000.e7. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

お問い合わせ在庫あり

Other size

お問い合わせ