INDOPY-1
INDOPY-1 (Indolopyridone-1) is a selective, reversible, and competitive HIV-1 reverse transcriptase inhibitor. INDOPY-1 reversibly binds to the active site of reverse transcriptase. INDOPY-1 inhibits DNA synthesis. INDOPY-1 exhibits antiviral activity against various retroviruses, including HIV-1 IIIB, HIV-1 HXB2 K103N Y181C, HIV-2 ROD, and SIV Mac251. INDOPY-1 can be used in the research of immunodeficiency virus infection.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 352548-47-1
- 分子式: C19H12N4O3
- 分子量:344.32
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
[1]|
HIV-1 |
HIV-2 |
体外実験
INDOPY-1 inhibits DNA synthesis, with an IC50 of 0.29 μM measured using Poly (rA) · poly (dT) and an IC50 of 1.1 μM measured using Poly (rI) · poly (dC)[1].
INDOPY-1 exhibits antiviral activity against diverse retroviruses, including HIV-1 IIIB, HIV-1 HXB2 K103N Y181C, HIV-2 ROD, and SIV Mac251[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 352548-47-1
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分子量 344.32
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分子式 C19H12N4O3
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SMILES
N#CC(C(N1C2=CC=C([N+]([O-])=O)C=C2)=O)=CC(N3C)=C1C4=C3C=CC=C4
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別名
Indolopyridone-1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
INDOPY-1 関連分類
HY-182474 関連分類
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