IPM-N001
IPM-N001 is a carbonic anhydrase IX (CAIX) ligand with a Kd value of <0.0337 nM for hCAIX. When radio-conjugated with 68Ga, IPM-N001 serves as a CAIX-targeted radionuclide tracer. [68Ga]Ga-IPM-N001 exhibits excellent tumor uptake and significantly improves the tumor-to-background ratio in PET/CT imaging studies using OS-RC-2 tumor-bearing mice. IPM-N001 can be used for the research of clear cell renal cell carcinoma.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C99H140N24O31S3
- 分子量:2258.51
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Radionuclide-Drug Conjugates (RDCs) アイソフォーム固有の製品をすべて表示
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生物活性
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hCA IX <0.0337 nM (Kd) |
IPM-N001 exhibits high binding affinity for purified hCAIX, with a Kd value of <0.0337 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 2258.51
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分子式 C99H140N24O31S3
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SMILES
NC([C@@H](NC([C@H](CO)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H]([C@@H](C)O)CC([C@H](CC(C)C)NC([C@@H](NC([C@H](CC(O)=O)NC([C@@H]3N(C([C@H](CCC(O)=O)N4)=O)CCC3)=O)=O)CC5=CC=CC(NC(CCCS(N)(=O)=O)=O)=C5)=O)=O)=O)=O)=O)CSCC6=CC(CSC[C@H](NC([C@H](CCC(NCCCN7C=CN=C7[N+]([O-])=O)=O)NC(CN8CCN(C(CN9CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC9)=O)CC8)=O)=O)C4=O)=CC=C6)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
IPM-N001 関連分類
HY-P11737 関連分類
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