Mefruside
Based on 1 Customer Validation
Mefruside is an orally active diuretic and has a mild hypotensive effect. Mefruside inhibits the synthesis of urea in an isolated rat liver perfusion model. Mefruside can be used in studies of oedema and hypertension.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.9%
- CAS 番号: 7195-27-9
- 分子式: C13H19ClN2O5S2
- 分子量:382.88
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Mefruside (0.3 mM; 50 min) shows 34% inhibition of urea synthesis in isolated perfused rat liver[1].
Mefruside (0.25, 0.5, 0.75, 1, 1.25 mM) inhibits urea synthesis in a concentration-dependent manner in isolated perfused rat liver[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Rat liver (from male Wistar rats of 120-220 g body weight; isolated perfused model)
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Concentration:0.3 mM
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Incubation Time:50 min
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Result:Exhibited inhibition rate of urea synthesis of 34%.
化学情報
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CAS 番号 7195-27-9
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性状 Solid
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分子量 382.88
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分子式 C13H19ClN2O5S2
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Color White to off-white
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SMILES
O=S(C1=CC=C(C(S(=O)(N)=O)=C1)Cl)(N(CC2(OCCC2)C)C)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
純度とドキュメンテーション
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データシート (269 KB)
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SDS (557 KB)
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- Français - FR (557 KB)
- Deutsch - DE (557 KB)
- Norwegian - NO (557 KB)
- Español - ES (557 KB)
- Swedish - SV (557 KB)
- Italian - IT (557 KB)
- Korean - KR (557 KB)
- Portuguese - PT (557 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Häussinger D, et al. Liver carbonic anhydrase and urea synthesis. Hepatology. 1988 Mar-Apr;8(2):435. [Content Brief]
[2]. Brogden RN, et al. Mefruside: a preliminary report of its pharmacological properties and therapeutic efficacy in oedema and hypertension. Drugs. 1974;7(6):419-25. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Mefruside 関連分類
HY-123179 関連分類
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