ML189
ML189 is an HSP90 inhibitor. ML189 can be used in the research of infectious diseases such as candidiasis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 337328-21-9
- 分子式: C20H17Cl2N3O
- 分子量:386.27
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
IC50 & Target
[1]|
HSP90 |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| NIH3T3 | IC50 |
21 μM
Compound: 1, ML189
|
Cytotoxicity in mouse NIH/3T3 cells after 48 hrs by Almar blue fluorimetry
Cytotoxicity in mouse NIH/3T3 cells after 48 hrs by Almar blue fluorimetry
|
[PMID: 21802942] |
化学情報
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CAS 番号 337328-21-9
-
分子量 386.27
-
分子式 C20H17Cl2N3O
-
SMILES
O=C(C1=CC=C(Cl)C=C1)N2CCN(C3=CC=NC4=CC(Cl)=CC=C34)CC2
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Hartland CL, et al. Identification of small molecules that selectively inhibit fluconazole-resistant Candida albicans in the presence of fluconazole but not in its absence. 2010 Oct 29. [Content Brief]
[2]. Tian J, et al. Overcoming matrix effects: GC method development for the determination of triethylamine and dimethyl sulfoxide in a drug substance. J Chromatogr Sci. 2014 Jan;52(1):36-41. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)