MS1 peptide
MS-1 peptide is a peptide for BH3 profiling. MS-1 peptide triggers higher depolarization of mitochondrial membrane in melanoma cells pre-treated with Encorafenib (HY-15605). MS1 peptide can be used for the research of BRAFV600E melanoma.
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- CAS 番号: 1875102-20-7
- 分子式: C126H197N39O35S
- 分子量:2850.22
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Bcl-2 |
MS1 peptide (4-8 μM) significantly increases mitochondrial membrane depolarization in encorafenib-pretreated DMBC11, DMBC12, DMBC21, DMBC28, and DMBC29 BRAFV600E melanoma cells, indicating altered cell dependence on anti-apoptotic proteins after encorafenib exposure[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1875102-20-7
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分子量 2850.22
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分子式 C126H197N39O35S
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配列
Ac-Arg-Pro-Glu-Ile-Trp-Met-Thr-Gln-Gly-Leu-Arg-Arg-Leu-Gly-Asp-Glu-Ile-Asn-Ala-Tyr-Tyr-Ala-Arg-NH2
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シーケンスの短縮
Ac-RPEIWMTQGLRRLGDEINAYYAR-NH2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
MS1 peptide 関連分類
HY-P11706 関連分類
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