Podentamig
Based on 1 Customer Validation
Podentamig (HPN 217) is a trispecific construct with three binding domains, including an anti-CD3 domain for T cell activation, an anti-BCMA domain for binding to plasma cells, and an anti-albumin domain for half-life extension. Podentamig is applicable to research related to relapsed/refractory multiple myeloma.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.66%
- CAS 番号: 2851863-52-8
- 分子量:53.48 kDa
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Isotype
VH-VH'-(scFv-heavy-lambda)
Species Reactivity
Human
IC50 & Target
CD3E/TNFRSF17[1]
体外実験
Podentamig has three binding domains, including an anti-CD3 domain for T cell activation, an anti-BCMA domain for binding to plasma cells, and an anti-albumin domain for half-life extension[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
遺伝子ID
アクセッション番号
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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VH-VH-scFvhl
アプリケーション
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized CD3D-CD3E Heterodimer Protein, Human (HEK293, HY-P77610) can bind Podentamig, The ED50 for this effect is 17.29 ng/mL. -
Immobilized BCMA/TNFRSF17 Protein, Human (HEK293, HY-P70827) can bind Podentamig, The ED50 for this effect is 395.8 ng/mL.
化学情報
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CAS 番号 2851863-52-8
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性状 Liquid
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分子量 53.48 kDa
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Color Colorless to light yellow
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SMILES
[Podentamig]
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別名
HPN 217
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輸送条件
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
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データシート (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)