SAR 97276
Based on 1 Customer Validation
SAR 97276 (Albitiazolium bromide) is an antimalarial agent. SAR 97276 interfers with the phospholipid metabolism of malarial parasites, especially the biosynthesis of phosphatidylcholine (PC). SAR 97276 enters erythrocytes through the new permeability pathways (NPP) of infected erythrocytes, and is transported into the malarial parasite by a poly-specific cation carrier.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.05%
- CAS 番号: 321915-72-4
- 分子式: C24H42Br2N2O2S2
- 分子量:614.54
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
製品説明
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Jurkat | IC50 |
347 μM
Compound: T3
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Cytotoxicity against human Jurkat cells after 24 hrs by [3H]thymidine incorporation assay
Cytotoxicity against human Jurkat cells after 24 hrs by [3H]thymidine incorporation assay
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[PMID: 23289711] |
化学情報
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CAS 番号 321915-72-4
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性状 Solid
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分子量 614.54
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分子式 C24H42Br2N2O2S2
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Color Off-white to light brown
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SMILES
OCCC1=C(C)[N+](CCCCCCCCCCCC[N+]2=CSC(CCO)=C2C)=CS1.[Br-].[Br-]
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別名
Albitiazolium bromide
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (162.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6272 mL | 8.1362 mL | 16.2723 mL | 40.6808 mL |
| 5 mM | 0.3254 mL | 1.6272 mL | 3.2545 mL | 8.1362 mL | |
| 10 mM | 0.1627 mL | 0.8136 mL | 1.6272 mL | 4.0681 mL | |
| 15 mM | 0.1085 mL | 0.5424 mL | 1.0848 mL | 2.7121 mL | |
| 20 mM | 0.0814 mL | 0.4068 mL | 0.8136 mL | 2.0340 mL | |
| 25 mM | 0.0651 mL | 0.3254 mL | 0.6509 mL | 1.6272 mL | |
| 30 mM | 0.0542 mL | 0.2712 mL | 0.5424 mL | 1.3560 mL | |
| 40 mM | 0.0407 mL | 0.2034 mL | 0.4068 mL | 1.0170 mL | |
| 50 mM | 0.0325 mL | 0.1627 mL | 0.3254 mL | 0.8136 mL | |
| 60 mM | 0.0271 mL | 0.1356 mL | 0.2712 mL | 0.6780 mL | |
| 80 mM | 0.0203 mL | 0.1017 mL | 0.2034 mL | 0.5085 mL | |
| 100 mM | 0.0163 mL | 0.0814 mL | 0.1627 mL | 0.4068 mL |
SAR 97276 関連分類
HY-14830 関連分類
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