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Tilrekimig

(別名: PF-07275315)
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Based on 1 Customer Validation

Tilrekimig (PF-07275315) is a monoclonal antibody targeting human interleukin-4 (IL-4), interleukin-13 (IL-13) and thymic stromal lymphopoietin (TSLP). Tilrekimig can be used in the research of allergic and inflammatory diseases, such as asthma and atopic dermatitis.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 純度 : 97.00%
  • CAS 番号: 2981469-90-1
  • 分子量:193.681 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Tilrekimig
  • Experimental Validation Results for Tilrekimig
  • Experimental Validation Results for Tilrekimig
  • Experimental Validation Results for Tilrekimig
  • Experimental Validation Results for Tilrekimig
  • Experimental Validation Results for Tilrekimig
  • Tilrekimig Chemical Structure
    Tilrekimig 構造式
CAS 番号: 2981469-90-1
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Fab-kappa_IgG1-kappa-lambda_disulfide

  • 1/16

    Loaded Tilrekimig on ProA biosensor, can bind HY-P70764 IL-4 Protein, Human (HEK293, His) with an affinity constant of 3.074E-10 M as determined in BLI assay.

  • 1/16

    Loaded Tilrekimig on ProA biosensor, can bind HY-P70568 IL-13 Protein, Human (HEK293, His) with an affinity constant of 1.917E-09 M as determined in BLI assay.

  • 1/16

    Loaded Tilrekimig on ProA biosensor, can bind HY-P70818 TSLP Protein, Human (HEK293, His) with an affinity constant of 1.060E-09 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1X106 Ramos cells labeling IL-4 with Tilrekimig (HY-P991162, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Flow cytometric analysis of 1X106 Jurkat cells labeling TSLP with Tilrekimig (HY-P991162, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Tilrekimig Chemical Structure
    1/16
  • Tilrekimig
  • Loaded Tilrekimig on ProA biosensor, can bind HY-P70764 IL-4 Protein, Human (HEK293, His) with an affinity constant of 3.074E-10 M as determined in BLI assay.
  • Loaded Tilrekimig on ProA biosensor, can bind HY-P70568 IL-13 Protein, Human (HEK293, His) with an affinity constant of 1.917E-09 M as determined in BLI assay.
  • Loaded Tilrekimig on ProA biosensor, can bind HY-P70818 TSLP Protein, Human (HEK293, His) with an affinity constant of 1.060E-09 M as determined in BLI assay.
  • Flow cytometric analysis of 1X106 Ramos cells labeling IL-4 with Tilrekimig (HY-P991162, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Flow cytometric analysis of 1X106 Jurkat cells labeling TSLP with Tilrekimig (HY-P991162, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Fab-kappa_IgG1-kappa-lambda_disulfide