Triptoquinone B
Triptoquinone B ((+)-Triptoquinone B), a sesquiterpene alkaloid, is an interleukin-1 inhibitor. Triptoquinone B shows potent inhibitory activities against interleukin 1α and β releases for human peripheral mononuclear cells.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 142937-50-6
- 分子式: C20H26O4
- 分子量:330.42
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
IC50 & Target
[1]|
IL-1 |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
19.91 μM
Compound: 9
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Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
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[PMID: 27133593] |
| Bcap37 | IC50 |
13.29 μM
Compound: 9
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Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay
Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay
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[PMID: 27133593] |
| Hep 3B2 | IC50 |
25.98 μM
Compound: 9
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Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay
Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay
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[PMID: 27133593] |
| HepG2 | IC50 |
26.3 μM
Compound: 9
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Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
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[PMID: 27133593] |
| MCF7 | IC50 |
16.69 μM
Compound: 9
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Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
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[PMID: 27133593] |
| U-251 | IC50 |
>100 μM
Compound: 9
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Cytotoxicity against human U251 cells after 48 hrs by MTT assay
Cytotoxicity against human U251 cells after 48 hrs by MTT assay
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[PMID: 27133593] |
化学情報
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CAS 番号 142937-50-6
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分子量 330.42
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分子式 C20H26O4
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SMILES
O=C1C(C(C)C)=CC(C([C@@]2(C)CC3)=C1CC[C@@]2([H])[C@@](C)(CO)C3=O)=O
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別名
(+)-Triptoquinone B
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Triptoquinone B 関連分類
HY-N1120 関連分類
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