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United States

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製品番号: HY-N19903

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Verticilatin

Verticilatin is a prenylated diaryl ether derived from phytopathogenic fungi, acting as an antibacterial agent and biofilm inhibitor. Verticilatin exhibits no direct growth inhibitory activity against Gram-negative bacteria. Verticilatin effectively inhibits the growth of Gram-positive strains, including methicillin-sensitive/resistant Staphylococcus aureus and Enterococcus faecalis, and reduces the biofilm-forming ability of Gram-negative Stenotrophomonas maltophilia. Verticilatin can be used for infections caused by the aforementioned Gram-positive bacteria and biofilm infections caused by Stenotrophomonas maltophilia.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
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CAS 番号: 2243140-21-6
分子式: C₁₉H₂₂O₃
分子量:298.38

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Verticilatin 構造式

CAS 番号: 2243140-21-6

価格（税別）

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Antibiotic アイソフォーム固有の製品をすべて表示 :

体外実験

Verticilatin (4 mg/L) does not inhibit growth of Gram-negative bacteria, reduces biofilm formation in two Stenotrophomonas maltophilia strains by up to 63%, and potently inhibits growth of Gram-positive MSSA, MRSA, and Enterococcus faecalis strains with an MIC of 4 mg/L^[1].
Verticilatin (2a) (4 mg/L; 24 h) potently inhibits the growth of MSSA ATCC25923, MRSA GK2235, MRSA USA300, and Enterococcus faecalis ATCC29212 with an MIC of 4 mg/L for all tested strains^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 2243140-21-6
分子量 298.38
分子式 C₁₉H₂₂O₃
SMILES

OC1=CC(C)=CC(OC2=CC(C)=C(C/C=C(C)\C)C(O)=C2)=C1
Structure Classification
- Phenols
- Polyphenols
Initial Source
- Microorganisms
Staphylococcus aureus
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Boehlich G J. Synthesis of Diorcinols and C-acyl glycosidic compounds[D]. Staats-und Universitätsbibliothek Hamburg Carl von Ossietzky, 2022.

[2]. Boehlich GJ, et al. Total Synthesis of Anti-MRSA Active Diorcinols and Analogues. Chemistry (Weinheim an der Bergstrasse, Germany). 2020 Aug 06;26(44):9846-9850. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

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分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Verticilatin

Antibiotic アイソフォーム固有の製品をすべて表示