Y11
Based on 1 Customer Validation
Y11 inhibits the autophosphorylation of FAK1 by blocking the phosphorylation of Y397. Y11 increases the expression level of IL-6. Y11 is applicable for cancer research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.34%
- CAS 番号: 1086639-59-9
- 分子式: C8H17BrN4O
- 分子量:265.15
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
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IL-6 |
化学情報
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CAS 番号 1086639-59-9
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性状 Solid
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分子量 265.15
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分子式 C8H17BrN4O
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Color White to off-white
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SMILES
OCC[N+]12C[N@](C3)C[N@](C[N@]3C2)C1.[Br-]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 10 mg/mL (37.71 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Golubovskaya VM, et al. A small molecule inhibitor, 1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growth. J Med Chem. 2008;51(23):7405-7416. [Content Brief]
[2]. Keasey MP, et al. Blood vitronectin is a major activator of LIF and IL-6 in the brain through integrin-FAK and uPAR signaling. J Cell Sci. 2018;131(3):jcs202580. Published 2018 Feb 2. [Content Brief]
[3]. Roux-Osovitz MM, et al. Trapping, tagging and tracking: Tools for the study of proteins during early development of the sea urchin. Methods Cell Biol. 2019;151:283-304. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7715 mL | 18.8573 mL | 37.7145 mL | 94.2863 mL |
| 5 mM | 0.7543 mL | 3.7715 mL | 7.5429 mL | 18.8573 mL | |
| 10 mM | 0.3771 mL | 1.8857 mL | 3.7715 mL | 9.4286 mL | |
| 15 mM | 0.2514 mL | 1.2572 mL | 2.5143 mL | 6.2858 mL | |
| 20 mM | 0.1886 mL | 0.9429 mL | 1.8857 mL | 4.7143 mL | |
| 25 mM | 0.1509 mL | 0.7543 mL | 1.5086 mL | 3.7715 mL | |
| 30 mM | 0.1257 mL | 0.6286 mL | 1.2572 mL | 3.1429 mL |
Y11 関連分類
HY-103471 関連分類
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