DC-CPin711
Based on 1 Customer Validation
DC-CPin711 is a potent and selective inhibitor of CREB-binding protein (CBP) bromodomain with an IC50 of 0.0626 μM. DC-CPin711 arrests cell cycle at G1 phase and induces apoptosis.
For research use only. We do not sell to patients.
- Purity: 99.09%
- CAS No.: 2447559-21-7
- Formula: C23H22N4O2
- Molecular Weight:386.45
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
IC50: 0.0626 μM (CBP bromodomain)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CWR22R | IC50 |
13 μM
Compound: 17
|
Antiproliferative activity against human 22RV-1 cells incubated for 96 hrs by CellTiter-Glo luminescent assay
Antiproliferative activity against human 22RV-1 cells incubated for 96 hrs by CellTiter-Glo luminescent assay
|
[PMID: 33045661] |
| MV4-11 | IC50 |
1.2 μM
Compound: 17
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Antiproliferative activity against human MV4-11 cells incubated for 96 hrs by CellTiter-Glo luminescent assay
Antiproliferative activity against human MV4-11 cells incubated for 96 hrs by CellTiter-Glo luminescent assay
|
[PMID: 33045661] |
Chemical Information
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CAS No. 2447559-21-7
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Appearance Solid
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Molecular Weight 386.45
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Formula C23H22N4O2
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Color white
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SMILES
O=C(N1CCCC2=C1C=C(NC(C3=CC=CC(C4=CC=NC=C4)=C3)=O)C=C2)NC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)