Copy Link Print Information

Thapsigargin

142 Cited Publications
고객리뷰

Based on 142 publication(s) in Google Scholar

Thapsigargin, an endoplasmic reticulum (ER) stress inducer, is an inhibitor of microsomal Ca2+-ATPase. Thapsigargin efficiently inhibits coronavirus (HCoV-229E, MERS-CoV, SARS-CoV-2) replication in different cell types.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

  • Purity: 99.87%
  • CAS No.: 67526-95-8
  • 화학식: C34H50O12
  • 분자량:650.75
  • 보관:

    -20°C, sealed storage, away from moisture and light

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

  • Thapsigargin Chemical Structure
    Thapsigargin Chemical Structure
  • Experimental Validation Results for Thapsigargin
  • Experimental Validation Results for Thapsigargin
  • Experimental Validation Results for Thapsigargin
  • Experimental Validation Results for Thapsigargin
  • Experimental Validation Results for Thapsigargin
  • Experimental Validation Results for Thapsigargin
  • Experimental Validation Results for Thapsigargin
CAS No.: 67526-95-8
사이즈
가격
재고
수량
Amount: USD 0.00
Please select quantity
or
or

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
주변의 대리점 찾기 Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • 용액&용해도
  • 순도&문서
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) Thapsigargin

More
Customer Validation & Images
Cell Imaging/StainingFlow CytometryRT-PCRWB
  • WB
  • RT-PCR
  • WB
  • Cell Imaging/Staining
  • Flow Cytometry
  • WB
  • WB

All Calcium Channel Isoforms

More
Keywords
100 mg

견적 받기 해외재고보유

Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress 로그인
Register
Sign in to MedChemExpress
회원가입

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • Thapsigargin Chemical Structure
    Thapsigargin Chemical Structure
    1/16
  • 1/16

    Thapsigargin purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2024 Dec 30;9(1):367. [Abstract]

    Customer Validation
     Tunicamycin (0.1 μM; 18 h) significantly reduces the protein abundance of IRF2BP2 in LPS-stimulated macrophages in a BiP-dependent manner.

  • 1/16

    Thapsigargin purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2024 Dec 30;9(1):367. [Abstract]

    Customer Validation
     Tunicamycin (0.1 μM; 18 h) doesn't decrease the mRNA levels of Irf2bp2 in LPS-stimulated macrophages.

  • 1/16

    Thapsigargin purchased from MedChemExpress. Usage Cited in: Inflammation. 2025 Oct;48(5):3146-3155. [Abstract]

    Customer Validation
     The melanocytes were treated with TM (3 μM), thapsigargin (1 μM), or DTT (1 mM) for 24 h to induce ER stress.

  • 1/16

    Thapsigargin purchased from MedChemExpress. Usage Cited in: Inflammation. 2025 Oct;48(5):3146-3155. [Abstract]

    Customer Validation
     The melanocytes were treated with TM (3 μM), thapsigargin (1 μM), or DTT (1 mM) for 24 h to induce ER stress.

  • 1/16

    Thapsigargin purchased from MedChemExpress. Usage Cited in: Inflammation. 2025 Oct;48(5):3146-3155. [Abstract]

    Customer Validation
     The melanocytes were treated with TM (3 μM), thapsigargin (1 μM), or DTT (1 mM) for 24 h to induce ER stress. ER stress induced an increase in the apoptosis of melanocytes.

  • 1/16

    Thapsigargin purchased from MedChemExpress. Usage Cited in: Cell. 2024 Apr 25;187(9):2288-2304.e27. [Abstract]

    Customer Validation
     Thapsigargin (10 nM) increases p-PERK, p-eIF2α, and ATF4 expressions as well as CD8+ T cell death and dysfunction in human CD8+ T cells.

  • 1/16

    Thapsigargin purchased from MedChemExpress. Usage Cited in: Microbiol Spectr. 2022 Dec 21;10(6):e0328222. [Abstract]

    Customer Validation
     Both PK-15 and 3D4/21cells are transfected with MGF110-7L-expressing plasmids with an increasing dose or empty vector and treated with Thapsigargin (TG) as positive controls. TG significant increases the levels of phosphorylated eIF2a (P-eIF2a) and ATF4 protein in the cells.

  • Thapsigargin