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Cat. No.: HY-W700638

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Benafentrine

Benafentrine is a phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4) inhibitor with bronchodilator activity. Benafentrine has IC₅₀ values of 1.74 μM and 1.76 μM for guinea pig platelet PDE3 and neutrophil PDE4, respectively. Benafentrine can be used in research related to obstructive airway diseases.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 35135-01-4
화학식: C₂₃H₂₇N₃O₃
분자량:393.49

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Benafentrine Chemical Structure

CAS No.: 35135-01-4

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

IC₅₀ & Target

^[1]

PDE3

1.74 μM (IC₅₀)

PDE4

1.76 μM (IC₅₀)

All Phosphodiesterase (PDE) Isoforms :

In Vitro

Benafentrine (compound 2) inhibits guinea-pig platelet PDE3 and guinea-pig neutrophil PDE4 with comparable potency, with IC₅₀ values of 1.74 μM and 1.76 μM respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 35135-01-4
분자량 393.49
화학식 C₂₃H₂₇N₃O₃
SMILES

O(C)C=1C=C2C([C@]3([C@@](N=C2C4=CC=C(NC(C)=O)C=C4)(CCN(C)C3)[H])[H])=CC1OC
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Banner KH, et al. Dual PDE3/4 inhibitors as therapeutic agents for chronic obstructive pulmonary disease. Br J Pharmacol. 2009 Jul;157(6):892-906.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

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Benafentrine

All Phosphodiesterase (PDE) Isoforms

Biological Activity

제품 설명

IC50 & Target

In Vitro

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Benafentrine Related Classifications

HY-W700638 Related Classifications

Bioz

Keywords

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