eeAChE-IN-3
eeAChE-IN-3 (compound YS3g) is an orally active, potent EeAChE and IL-6 inhibitor with IC50s of 0.54 μM, 0.49 μM, 8.54 μM and 0.57 μM for EeAChE, RatAChE, RatBuChE and IL-6, respectively. eeAChE-IN-3 improves STZ (HY-13753) (Streptozotocin; HY-13753)-induced learning and memory impairment in mice. eeAChE-IN-3 has the potential for Alzheimer's disease (AD) research.
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- 화학식: C18H25N3O4
- 분자량:347.41
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
EeAChE 0.54 μM (IC50) |
RatAChE 0.49 μM (IC50) |
RatBuChE 8.54 μM (IC50) |
IL-6 0.57 μM (IC50) |
Chemical Information
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분자량 347.41
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화학식 C18H25N3O4
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SMILES
O=C1C2=C(OC)C=C(OC)C=C2OC(CCCNN3CCNCC3)=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)