Eugenitin
Eugenitin is a polyketide isolated from the fungus Mycoleptodiscus indicus that is related to the South American medicinal plant. Eugenitin inhibits Leishmania major with LD50=39.9 μM. Eugenitin has low cytotoxicity (IC50 >131 μM) against several human cancer cell lines.
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- CAS No.: 480-12-6
- 화학식: C12H12O4
- 분자량:220.22
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
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Biological Activity
LD50: 39.9 μM (Leishmania major)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-8 | IC50 |
>113 μM
Compound: 3
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Cytotoxicity against human HCT8 cells by colorimetric method
Cytotoxicity against human HCT8 cells by colorimetric method
|
[PMID: 24387625] |
| HL-60 | IC50 |
>113 μM
Compound: 3
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Cytotoxicity against human HL60 cells by colorimetric method
Cytotoxicity against human HL60 cells by colorimetric method
|
[PMID: 24387625] |
| Lymphocyte | IC50 |
>113 μM
Compound: 3
|
Cytotoxicity against human lymphocytes by colorimetric method
Cytotoxicity against human lymphocytes by colorimetric method
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[PMID: 24387625] |
| MDA-MB-435 | IC50 |
>113 μM
Compound: 3
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Cytotoxicity against human MDA-MB-435 cells by colorimetric method
Cytotoxicity against human MDA-MB-435 cells by colorimetric method
|
[PMID: 24387625] |
| PC-3 | IC50 |
>113 μM
Compound: 3
|
Cytotoxicity against human PC3 cells by colorimetric method
Cytotoxicity against human PC3 cells by colorimetric method
|
[PMID: 24387625] |
| SF-295 | IC50 |
>113 μM
Compound: 3
|
Cytotoxicity against human SF295 cells by colorimetric method
Cytotoxicity against human SF295 cells by colorimetric method
|
[PMID: 24387625] |
Chemical Information
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CAS No. 480-12-6
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분자량 220.22
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화학식 C12H12O4
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SMILES
O=C1C=C(C)OC2=C1C(O)=C(C)C(OC)=C2
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Structure Classification
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Initial Source
Mycoleptodiscus indicus
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)