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United States

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Cat. No.: HY-180936

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FBPase-IN-6

FBPase-IN-6 (Compound 96) is an orally active FBPase inhibitor with an IC₅₀ value of 1.769 μM. FBPase-IN-6 modulates AMPK/mTORC1/S6K signaling pathways. FBPase-IN-6 improves glucose tolerance, enhances insulin sensitivity, and promotes insulin secretion in type 2 diabetic mice.

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화학식: C₂₅H₂₄ClN₃O₅S
분자량:513.99

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

FBPase-IN-6 Chemical Structure

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

^[1]

mTORC1

All AMPK Isoforms :

All mTOR Isoforms :

All Ribosomal S6 Kinase (RSK) Isoforms :

Chemical Information

분자량 513.99
화학식 C₂₅H₂₄ClN₃O₅S
SMILES

COC1=CC=CC(NC2=C3C(N(C)C(C(N(C)S(C4=CC=C(OC)C=C4)(=O)=O)=O)=C3)=C(Cl)C=C2)=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Xu K, et al. Beneficial Effects of a Novel Fructose-1, 6-Bisphosphatase Inhibitor Cpd96 on Insulin Secretion in Type 2 Diabetes. ACS Pharmacology & Translational Science, 2025.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

FBPase-IN-6

All AMPK Isoforms

All mTOR Isoforms

All Ribosomal S6 Kinase (RSK) Isoforms

Biological Activity

제품 설명

IC50 & Target

Chemical Information

순도&문서

References

Calculators

Help & FAQs

FBPase-IN-6 Related Classifications

HY-180936 Related Classifications

Bioz

Keywords

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