Flutropium bromide
Flutropium bromide (Ba 598Br) is a organic bromide salt of flutropium. Flutropium bromide shows an anticholinergic effect. Flutropium bromide effectively suppresses spasms and it can be used for the research of asthma and chronic obstructive pulmonary disease.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 63516-07-4
- 화학식: C24H29BrFNO3
- 분자량:478.39
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
In Vitro
Flutropium bromide is more effective than atropine in vitro experiments[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Guinea pigs[2]
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Dosage:3 and 10 mg/kg
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Administration:Intravenous injection; 3 and 10 mg/kg once
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Result:Showed an inhibitory action on the 48 hours homologous PCA and inhibited the release of histamine from isolated rat mast cells stimulated by antigen in guinea pigs.
Chemical Information
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CAS No. 63516-07-4
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분자량 478.39
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화학식 C24H29BrFNO3
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SMILES
FCC[N@@+]([C@@H](CC1)C2)(C)[C@H]1C[C@@H]2OC(C(C3=CC=CC=C3)(C4=CC=CC=C4)O)=O.[Br-]
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Synonyms
Ba 598Br; Flubron
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Mizuno H, et al. [Effects of flutropium bromide, a new anti-asthma drug, alone or in combination with salbutamol, aminophylline and disodium cromoglycate on the acetylcholine induced bronchoconstriction]. Nihon Yakurigaku Zasshi. 1990 Jan;95(1):31-40. [Content Brief]
[2]. Misawa M, et al. [Effects of flutropium bromide, a new antiasthma drug, on mediator release from mast cells and actions of mediators]. Nihon Yakurigaku Zasshi. 1988 Feb;91(2):97-103. Japanese. [Content Brief]
[3]. Bauer R, Fügner A. Pharmacology of the anticholinergic bronchospasmolytic agent flutropium bromide. Arzneimittelforschung. 1986 Sep;36(9):1348-52. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Flutropium bromide Related Classifications
HY-106564A Related Classifications
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