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Galiximab

(Synonyms: IDEC 114; Anti-Human CD80 Recombinant Antibody)
1 Cited Publications
고객리뷰

Based on 1 publication(s) in Google Scholar

Galiximab (IDEC-114) is a primatized monoclonal IgG1 antibody targeting CD80. Galiximab variable regions are primatized, and the constant regions are humanized. Galiximab induces antibody-dependent cellular cytotoxicity by blocking CD80-CD28 binding. Galiximab has antitumor activity and can induce apoptosis in tumor cells. Galiximab can be used in the research of relapsed Hodgkin lymphoma and solid tumors.

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  • Purity: 99.23%
  • CAS No.: 357613-77-5
  • 분자량:145.24 kDa
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Galiximab
  • Experimental Validation Results for Galiximab
  • Experimental Validation Results for Galiximab
  • Galiximab Chemical Structure
    Galiximab Chemical Structure
CAS No.: 357613-77-5
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Galiximab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
주변의 대리점 찾기 Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 lambda

  • 1/16

    Immobilized B7-1/CD80 Protein, Human (HEK293, HY-P70651) can bind Galiximab, The ED50 for this effect is 2.33 ng/mL.

  • 1/16

    Flow Cytometry analysis of Raji cells labelling CD28L/CD80 (red) with Galiximab (anti-CD28L/CD80) (HY-P99293). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.

  • Galiximab Chemical Structure
    1/16
  • Galiximab
  • Immobilized B7-1/CD80 Protein, Human (HEK293, HY-P70651) can bind Galiximab, The ED50 for this effect is 2.33 ng/mL.
  • Flow Cytometry analysis of Raji cells labelling CD28L/CD80 (red) with Galiximab (anti-CD28L/CD80) (HY-P99293). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.