GE 2270A
GE 2270A (MDL 62879) is an antibiotic. GE 2270A inhibits gram-positive bacteria and anaerobes by inhibiting protein synthesis. GE 2270A can be used for the research of infection.
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- CAS No.: 134861-34-0
- 화학식: C56H55N15O10S6
- 분자량:1290.52
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
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Biological Activity
IC50: 0.4 μM (poly(U)-directed poly(Phe) synthesis)[2]
GE 2270A (0.01-100 mg/L) inhibits poly(U)-directed poly(Phe) synthesis in cell-free systems with an IC50 value of 0.12 mg/L[1]. GE 2270A (0-0.1 mM; 10 min) is a strong inhibitor of protein biosynthesis in vitro as determined in a minimal E. coli purified system for poly(U)-directed poly(Phe) synthesis with an IC50 value of 0.4 μM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 134861-34-0
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분자량 1290.52
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화학식 C56H55N15O10S6
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Synonyms
MDL 62879
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Landini P, B et al. Inhibition of bacterial protein synthesis by elongation-factor-Tu-binding antibiotics MDL 62,879 and efrotomycin. Biochem J. 1992 May 1;283 ( Pt 3)(Pt 3):649-52. [Content Brief]
[2]. Anborgh PH, Parmeggiani A. New antibiotic that acts specifically on the GTP-bound form of elongation factor Tu. EMBO J. 1991 Apr;10(4):779-84. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GE 2270A Related Classifications
HY-106882 Related Classifications
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