IPM-N001
IPM-N001 is a carbonic anhydrase IX (CAIX) ligand with a Kd value of <0.0337 nM for hCAIX. When radio-conjugated with 68Ga, IPM-N001 serves as a CAIX-targeted radionuclide tracer. [68Ga]Ga-IPM-N001 exhibits excellent tumor uptake and significantly improves the tumor-to-background ratio in PET/CT imaging studies using OS-RC-2 tumor-bearing mice. IPM-N001 can be used for the research of clear cell renal cell carcinoma.
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- 화학식: C99H140N24O31S3
- 분자량:2258.51
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
All Radionuclide-Drug Conjugates (RDCs) Isoforms
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Biological Activity
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hCA IX <0.0337 nM (Kd) |
IPM-N001 exhibits high binding affinity for purified hCAIX, with a Kd value of <0.0337 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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분자량 2258.51
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화학식 C99H140N24O31S3
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SMILES
NC([C@@H](NC([C@H](CO)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H]([C@@H](C)O)CC([C@H](CC(C)C)NC([C@@H](NC([C@H](CC(O)=O)NC([C@@H]3N(C([C@H](CCC(O)=O)N4)=O)CCC3)=O)=O)CC5=CC=CC(NC(CCCS(N)(=O)=O)=O)=C5)=O)=O)=O)=O)=O)CSCC6=CC(CSC[C@H](NC([C@H](CCC(NCCCN7C=CN=C7[N+]([O-])=O)=O)NC(CN8CCN(C(CN9CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC9)=O)CC8)=O)=O)C4=O)=CC=C6)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IPM-N001 Related Classifications
HY-P11737 Related Classifications
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