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Cat. No.: HY-158060

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MC2646

MC2646 is a potent anti-parasite agent. MC2646 induces autophagic. MC2646 activates the AMPK/TFEB pathway.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₂₁H₂₀N₂O
분자량:316.40

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

MC2646 Chemical Structure

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

MC2646 is a potent anti-parasite agent. MC2646 induces autophagic. MC2646 activates the AMPK/TFEB pathway^[1].

All Parasite Isoforms :

In Vitro

MC2646 (4 µM; 24 h) induces autophagic flux by increases the LC3-II:LC3-I ratio ^[1].
MC2646 (4 µM; 24 h) increases the expression of p-AMPK and increase in the nuclear:cytoplasmic TFEB localization^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis^[1]

Cell Line:

TBL3, BL3 cells
Concentration:

4 µM
Incubation Time:

24 h
Result:

Increased the LC3-II:LC3-I ratio in infected TBL3 and uninfected BL3 cells,

Chemical Information

분자량 316.40
화학식 C₂₁H₂₀N₂O
SMILES

NC1CC1C2=CC=C(C=C2)NC(CC3=CC4=CC=CC=C4C=C3)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Villares M, et al. Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy. Nat Commun. 2024 Mar 12;15(1):2235. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

MC2646

All Parasite Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

MC2646 Related Classifications

HY-158060 Related Classifications