Morachalcone A
Morachalcone A is a naturally-occurring aromatase inhibitor (IC50=4.6 mM). Morachalcone A is also a plants metabolite with potential anti-inflammatory and anticancer activity. Morachalcone A inhibits Lipopolysaccharide (HY-D1056)-induced nitric oxide production.
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- CAS No.: 76472-88-3
- 화학식: C20H20O5
- 분자량:340.37
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
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Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
16.4 μM
Compound: 3
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Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells assessed as nitrite accumulation after 20 hrs
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells assessed as nitrite accumulation after 20 hrs
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[PMID: 16643064] |
| RAW264.7 | IC50 |
58 μM
Compound: 3
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Cytotoxicity against mouse RAW264.7 cells by MTT assay
Cytotoxicity against mouse RAW264.7 cells by MTT assay
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[PMID: 16643064] |
In Vitro
Morachalcone A is the metabolite of Maclura pomifera (the Osage orange tree) and Hypericum Geminiflorum and Broussonetia papyrifera[1].
Morachalcone A exhibites inhibitory activities against lipopolysaccharide-induced nitric oxide production in cultured RAW 264.7 cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 76472-88-3
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분자량 340.37
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화학식 C20H20O5
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SMILES
OC(C=C(O)C=C1)=C1/C=C/C(C2=C(C(C/C=C(C)/C)=C(O)C=C2)O)=O
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Morachalcone A Related Classifications
HY-N3246 Related Classifications
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