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Cat. No.: HY-15101

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MV061194

MV061194 is a selective cathepsin K inhibitor with a human K_i of 2.5 nM. MV061194 can be used for the research of osteoporosis.

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CAS No.: 1021423-50-6
화학식: C₂₈H₃₇N₅O₄S
분자량:539.70

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

MV061194 Chemical Structure

CAS No.: 1021423-50-6

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

MV061194 is a selective cathepsin K inhibitor with a human K_i of 2.5 nM. MV061194 can be used for the research of osteoporosis^[1].

IC₅₀ & Target^[1]

cathepsin K

2.5 nM (Ki)

All Cathepsin Isoforms :

In Vitro

MV061194 potently and selectively inhibits recombinant human cathepsin K with a K_i of 2.5 nM, showing >4000-fold selectivity over multiple other cathepsin isoforms^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1021423-50-6
분자량 539.70
화학식 C₂₈H₃₇N₅O₄S
SMILES

C(N[C@H]1[C@H](CC)OCC1=O)(=O)C2(NC(=O)C3=CC=C(C=C3)C=4N=C(SC4)N5CCN(C)CC5)CCCCC2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Allen J G, et al. Emerging targets in osteoporosis disease modification[J]. Journal of medicinal chemistry, 2010, 53(11): 4332-4353. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
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MV061194

All Cathepsin Isoforms