Oleoyl serotonin
Based on 1 Customer Validation
Oleoyl Serotonin (compound 1e) is a TRPV1 antagonist with IC50 value of 2.57 μM for human TRPV1.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 98.28%
- CAS No.: 1002100-44-8
- 화학식: C28H44N2O2
- 분자량:440.66
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보관:
Solution, -20°C, 2 years
Biological Activity
제품 설명
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
2.57 μM
Compound: 1e
|
Antagonist activity at human recombinant TRPV1 receptor expressed in HEK293 cells assessed as inhibition of capsaicin-induced intracellular calcium elevation
Antagonist activity at human recombinant TRPV1 receptor expressed in HEK293 cells assessed as inhibition of capsaicin-induced intracellular calcium elevation
|
[PMID: 18027904] |
Chemical Information
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CAS No. 1002100-44-8
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Appearance Liquid
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분자량 440.66
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화학식 C28H44N2O2
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Color Colorless to light yellow
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SMILES
CCCCCCCC/C=C\CCCCCCCC(NCCC1=CNC2=C1C=C(O)C=C2)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Solution, -20°C, 2 years
Protocol
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
순도&문서
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Data Sheet (260 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)