PDE4-IN-29
PDE4-IN-29 (Compound 55) is an orally active and selective PDE4 inhibitor (including subtypes such as PDE4A1, PDE4B2, PDE4D3) with IC50s of <5 nM against PDE4D3. PDE4-IN-29 inhibits the degradation of cyclic adenosine monophosphate (cAMP), increases intracellular cAMP levels, suppressing the release of inflammatory factors such as TNF-α. PDE4-IN-29 is promising for research of inflammatory diseases including psoriasis, atopic dermatitis, and chronic obstructive pulmonary disease.
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- CAS No.: 2815361-45-4
- 화학식: C27H34N2O8S
- 분자량:546.63
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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PDE4A1 |
PDE4B2 |
PDE4D3 |
Chemical Information
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CAS No. 2815361-45-4
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분자량 546.63
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화학식 C27H34N2O8S
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SMILES
O=C1N([C@@H](C2=CC(OCC)=C(OC)C=C2)CS(C)(=O)=O)C(C3=C(NC(C)=O)C=CC(C(CCCC)O)=C31)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PDE4-IN-29 Related Classifications
HY-176520 Related Classifications
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