PF-4178903
PF-4178903 (INCB10820) is an orally active, potent dual CCR2 and CCR5 antagonist with IC50 values of 3 nM and 5.3 nM, respectively. PF-4178903 is promising for research of chronic inflammatory and autoimmune diseases.
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- CAS No.: 1310796-72-5
- 화학식: C25H37F3N4O3
- 분자량:498.58
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
IC50 & Target
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CCR2 3 nM (IC50) |
CCR5 5.3 nM (IC50) |
Chemical Information
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CAS No. 1310796-72-5
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분자량 498.58
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화학식 C25H37F3N4O3
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SMILES
O=C(N1CCN(C2=CC(C(F)(F)F)=CC=N2)CC1)[C@@]3(C[C@@H](CC3)N[C@@H]4[C@@H](COCC4)OC)C(C)C
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Synonyms
INCB10820
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)