Umifoxolaner
Based on 1 Customer Validation
Umifoxolaner (ML-878), a γ-aminobutyric acid (GABA) regulated chloride channels antagonist, is a potent insecticide, and acaricide. Umifoxolaner can be uesd for parasite infection research.
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- Purity: 99.97%
- CAS No.: 2021230-37-3
- 화학식: C26H16ClF10N3O3
- 분자량:643.86
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보관:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
All Parasite Isoforms
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Biological Activity
Chemical Information
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CAS No. 2021230-37-3
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Appearance Solid
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분자량 643.86
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화학식 C26H16ClF10N3O3
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Color White to off-white
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SMILES
FC(F)([C@@]1(C2=CC(C(F)(F)F)=C(C(Cl)=C2)F)CC(C3=CC=C(C(NCC(NCC(F)(F)F)=O)=O)C4=C3C=CC=C4)=NO1)F
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Synonyms
ML-878
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선적
Room temperature in continental US; may vary elsewhere.
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보관
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
용액&용해도
DMSO : 100 mg/mL (155.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
순도&문서
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5531 mL | 7.7657 mL | 15.5313 mL | 38.8283 mL |
| 5 mM | 0.3106 mL | 1.5531 mL | 3.1063 mL | 7.7657 mL | |
| 10 mM | 0.1553 mL | 0.7766 mL | 1.5531 mL | 3.8828 mL | |
| 15 mM | 0.1035 mL | 0.5177 mL | 1.0354 mL | 2.5886 mL | |
| 20 mM | 0.0777 mL | 0.3883 mL | 0.7766 mL | 1.9414 mL | |
| 25 mM | 0.0621 mL | 0.3106 mL | 0.6213 mL | 1.5531 mL | |
| 30 mM | 0.0518 mL | 0.2589 mL | 0.5177 mL | 1.2943 mL | |
| 40 mM | 0.0388 mL | 0.1941 mL | 0.3883 mL | 0.9707 mL | |
| 50 mM | 0.0311 mL | 0.1553 mL | 0.3106 mL | 0.7766 mL | |
| 60 mM | 0.0259 mL | 0.1294 mL | 0.2589 mL | 0.6471 mL | |
| 80 mM | 0.0194 mL | 0.0971 mL | 0.1941 mL | 0.4854 mL | |
| 100 mM | 0.0155 mL | 0.0777 mL | 0.1553 mL | 0.3883 mL |
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