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  3. Akt Arginase Bacterial Isotope-Labeled Compounds
  4. L-Valine-d1

L-Valine-d1  (Synonyms: (S)-Valine-d1)

Cat. No.: HY-N0717S8 Purity: 98.0%
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Handling Instructions Technical Support

L-Valine-d1 ((S)-Valine-d1) is the deuterium labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase.

For research use only. We do not sell to patients.

L-Valine-d<sub>1</sub>

L-Valine-d1 Chemical Structure

CAS No. : 77257-03-5

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
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Solution
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Solid
5 mg In-stock
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Other Forms of L-Valine-d1:

L-Valine-d1 Related Antibodies

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Description

L-Valine-d1 ((S)-Valine-d1) is the deuterium labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase[1][2][3].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-Valine-d1 Related Antibodies
Molecular Weight

118.15

Formula

C5H10DNO2
CAS No.
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

CC(C)[C@@](N)([2H])C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 17.5 mg/mL (148.12 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.4638 mL 42.3191 mL 84.6382 mL
5 mM 1.6928 mL 8.4638 mL 16.9276 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 8.4638 mL 42.3191 mL 84.6382 mL 211.5954 mL
5 mM 1.6928 mL 8.4638 mL 16.9276 mL 42.3191 mL
10 mM 0.8464 mL 4.2319 mL 8.4638 mL 21.1595 mL
15 mM 0.5643 mL 2.8213 mL 5.6425 mL 14.1064 mL
20 mM 0.4232 mL 2.1160 mL 4.2319 mL 10.5798 mL
25 mM 0.3386 mL 1.6928 mL 3.3855 mL 8.4638 mL
30 mM 0.2821 mL 1.4106 mL 2.8213 mL 7.0532 mL
40 mM 0.2116 mL 1.0580 mL 2.1160 mL 5.2899 mL
50 mM 0.1693 mL 0.8464 mL 1.6928 mL 4.2319 mL
60 mM 0.1411 mL 0.7053 mL 1.4106 mL 3.5266 mL
80 mM 0.1058 mL 0.5290 mL 1.0580 mL 2.6449 mL
100 mM 0.0846 mL 0.4232 mL 0.8464 mL 2.1160 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-Valine-d1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Valine-d177257-03-5(S)-Valine-d1AktArginaseBacterialIsotope-Labeled CompoundsPKBProtein kinase BInhibitorinhibitorinhibit

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