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Letolizumab

(Synonyms: BMS-986004)
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Based on 1 Customer Validation

Letolizumab (BMS-986004) is a monoclonal antibody targeting CD40L, which is produced to express mutant IgG1 lacking effector function, including Fc binding and complement fixation. Letolizumab reduces rejection, thromboembolism and prolongs the survival time.

For research use only. We do not sell to patients.

  • Purity: 98.32%
  • CAS No.: 1450981-87-9
  • Molecular Weight:78 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Letolizumab
  • Experimental Validation Results for Letolizumab
  • Letolizumab Chemical Structure
    Letolizumab Chemical Structure
CAS No.: 1450981-87-9
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609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    [G1 VH-h-CH2-CH3]-dimer

  • 1/16

    Flow cytometric analysis of 1X106 500 ng/mL anti-CD3 stimulated Jurkat cells(24h) with Letolizumab (HY-P99701, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Letolizumab Chemical Structure
    1/16
  • Letolizumab
  • Flow cytometric analysis of 1X106 500 ng/mL anti-CD3 stimulated Jurkat cells(24h) with Letolizumab (HY-P99701, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • [G1 VH-h-CH2-CH3]-dimer