- Lipids
- Octadecanoids
-
Octadecanoids (186)
- Formula: C18H34O3
- Molecular Weight: 298.46
3-Oxooctadecanoic acid (3-Oxostearic acid) is a saturated fatty acid (SFA). 3-Oxooctadecanoic acid is an intermediate product in fatty acid biosynthesis and it was converted from malonic acid via the enzyme.
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- Formula: C18H32O4
- Molecular Weight: 312.44
9(S)-HpODE is produced by the action of arachidonate 5-LO on linoleic acid. It can be further metabolized by potato hydroperoxide dehydratase to colneleic acid.
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- Formula: C18H30O2
- Molecular Weight: 278.43
Pinolenic acid (PNLA) is a polyunsaturated fatty acid that can be isolated from Pinus orientalis and Pinus pinaster seed oil. Pinolenic acid has anti-inflammatory and lipid-lowering activities.
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- Formula: C18H28O3
- Molecular Weight: 292.41
12-Oxo phytodienoic acid (≥90%) (12-OPDA (≥90%)) is a plant lipid-derived anti-inflammatory compound. 12-Oxo phytodienoic acid (≥90%) induces the expression of SOCS-1 and inhibits LPS (HY-D1056)-induced activation of the NF-κB and p38 MAPK signaling pathways. 12-Oxo phytodienoic acid (≥90%) inhibits LPS-induced expression of IL-6 and TNF-α, and reduces LPS-induced NO production by decreasing iNOS levels. 12-Oxo phytodienoic acid (≥90%) induces activation of the Nrf2 signaling cascade. 12-Oxo phytodienoic acid (≥90%) can be used for the research of neurodegenerative diseases.
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- Formula: C18H32O2
- Molecular Weight: 280.45
9-Octadecynoic acid is a DNA binding agent with a dissociation constant of 1.8 mM. 9-Octadecynoic acid is also an agonist for peroxisome proliferator-activated receptor γ (PPARγ).
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- Formula: C18H32O2
- Molecular Weight: 280.45
9(E),11(E)-Octadecadienoic acid is an isomer of conjugated linoleic acid (CLA). Conjugated linoleic acid is a fatty acid with potentially beneficial physiological and anticarcinogenic effects.
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- Formula: C18H31NO4
- Molecular Weight: 325.44
10-Nitrolinoleic acid is a potent peroxisome proliferator-activated receptor γ (PPARγ) agonist. 10-Nitrolinoleic acid competes with [3H]Rosiglitazone for binding to PPAR-γ, with an IC50 of 0.22 μM.
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- Formula: C18H34O3
- Molecular Weight: 298.46
13-Oxo-octadecanoic acid (13-Oxostearic acid) is an ester product.
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- Formula: C18H28O3
- Molecular Weight: 292.41
(9S,13R)-12-Oxo phytodienoic acid ((9S,13R)-12-OPDA) is a mPGES-1 inhibitor and Nrf2 activator. (9S,13R)-12-Oxo phytodienoic acid selectively inhibits mPGES-1 expression and reduces inducible PGE2 production without affecting COX-1 or COX-2. (9S,13R)-12-Oxo phytodienoic acid inhibits the phosphorylation of IKKβ, IκBα, and NF-κB (p65), blocks the nuclear translocation of p65, increases the nuclear translocation of Nrf2, and upregulates HO-1 expression. (9S,13R)-12-Oxo phytodienoic acid inhibits the differentiation of M0 macrophages toward the M1 phenotype and promotes differentiation toward the M2 phenotype. (9S,13R)-12-Oxo phytodienoic acid decreases the levels of NO, PGE2, IL-1β, IL-6, iNOS, and PGD2. (9S,13R)-12-Oxo phytodienoic acid can be used for inflammation research.
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- Formula: C18H29NO4
- Molecular Weight: 323.43
(-)-Jasmonoyl-L-isoleucine ((-)-JA-L-Ile) is an inactive hormone and jasmonic acid-amino acid conjugate, as well as a stereoisomer of (+)-7-iso-JA-L-Ile. (-)-Jasmonoyl-L-isoleucine fails to promote the formation of the COI1-JAZ protein complex. (-)-Jasmonoyl-L-isoleucine does not induce jasmonic acid-dependent phenotypic responses in Arabidopsis seedlings, including root growth inhibition and anthocyanin accumulation.
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- Formula: C12H18O3
- Molecular Weight: 210.27
Jasmonic acid ((-)-Jasmonic acid) is a plant growth regulator and a derivative of Linolenic acid (HY-N0728). Jasmonic acid enhances plant resistance and is widely used as a stress protectant. Jasmonic acid is an endogenous plant hormone and a plant growth inhibitor.
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- Formula: C18H32O3
- Molecular Weight: 296.44
(±)9-HODE is a racemate of 9-HODE. 9-HODE is a oxidized derivatives of Linoleic acid (HY-N0729).
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- Formula: C18H34O5
- Molecular Weight: 330.46
Pinellic acid is an orally active adjuvant for intranasal influenza vaccines. Pinellic acid can be extracted from the tubers of Pinellia ternata Breitenbach. When administered intranasally in combination with influenza HA vaccine, Pinellic acid slightly increases the titers of antiviral IgG antibodies in bronchoalveolar lavage fluid and serum. Pinellic acid shows no hemolytic activity. Pinellic acid can be used in studies related to influenza virus infection.
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- Formula: C18H34O2
- Molecular Weight: 282.46
trans-2-Octadecenoic acid is a biochemical reagent.
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- Formula: C18H30O4
- Molecular Weight: 310.43
13-Hydroxy-12-oxo-9(Z),15(Z)-octadecadienoic acid is a fatty acid.
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- Formula: C18H30O4
- Molecular Weight: 310.43
9-Hydroxy-10-oxo-12(Z),15(Z)-octadecadienoic acid ((12Z,15Z)-9-Hydroxy-10-oxooctadeca-12,15-dienoic acid) is an ester product.
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- Formula: C18H34O3
- Molecular Weight: 298.47
16-Oxo-octadecanoic acid is an octadecanoid.
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- Formula: C18H34O2
- Molecular Weight: 282.46
Petroselaidic acid is a trans fatty acid and the trans isomer of Petroselinic acid (HY-113362). Petroselaidic acid can be found in dairy products such as cow's milk and goat's milk.
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- Formula: C18H36O3
- Molecular Weight: 300.48
3-hydroxy Stearic acid is a long-chain saturated fatty acid and can be found in C. pyloridis.
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- Formula: C18H34O5
- Molecular Weight: 330.46
9(S)10(S)13(S)-TriHOME is an ester product.
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