Marumoside A
Marumoside A is a Phenols product that can be isolated from the leaves of Moringa oleifera.. Marumoside A suppresses the expression of IL-17A, and increases the expression of keratinocyte differentiation markers, thereby ameliorating psoriasis-like skin lesions. Marumoside A can ameliorates psoriasis-like skin lesions. Marumoside A can be used for the study of psoriasis.
For research use only. We do not sell to patients.
- CAS No.: 1309604-34-9
- Formula: C14H19NO6
- Molecular Weight:297.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 1309604-34-9
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Molecular Weight 297.30
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Formula C14H19NO6
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SMILES
O=C(N)CC1=CC=C(O[C@H]2[C@@H]([C@@H]([C@H]([C@H](C)O2)O)O)O)C=C1
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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RNA extraction experimental
By lysing cells, releasing RNA, and removing impurities such as proteins and DNA, high-purity RNA products are finally obtained. The commonly used traditional method is the guanidine isothiocyanate/phenol/chloroform method (Trizol), which is suitable for a variety of animal materials including animal tissues, microorganisms, cultured cells, etc., and most plant materials.
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Imiquimod-Induced Psoriasiform Dermatitis
Imiquimod (IMQ)-induced psoriasiform dermatitis is a widely used murine model in which topical application of IMQ, a Toll-like receptor 7 (TLR7) agonist, triggers innate immune activation in the skin and induces a psoriasis-like inflammatory cascade characterized by epidermal hyperplasia, immune cell infiltration, and cytokine production dominated by the IL-23/IL-17 axis. This inflammatory response is mediated through activation of dendritic cells and downstream induction of IL-23, IL-17A, IL-22, and related pro-inflammatory mediators, recapitulating key features of human plaque psoriasis and enabling mechanistic and therapeutic studies. The model is commonly induced using Aldara (5% IMQ cream) applied topically to murine skin, resulting in rapid onset of erythema, scaling, and thickening that can be quantified as disease severity indices and validated histologically.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Marumoside A Related Classifications
HY-N9047 Related Classifications
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