2. Autophagy Anti-infection
  3. Autophagy Parasite
  4. MC2646

MC2646 is a potent anti-parasite agent. MC2646 induces autophagic. MC2646 activates the AMPK/TFEB pathway.

For research use only. We do not sell to patients.

MC2646 Chemical Structure

MC2646 Chemical Structure

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MC2646 Related Antibodies

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Description

MC2646 is a potent anti-parasite agent. MC2646 induces autophagic. MC2646 activates the AMPK/TFEB pathway[1].

In Vitro

MC2646 (4 µM; 24 h) induces autophagic flux by increases the LC3-II:LC3-I ratio [1].
MC2646 (4 µM; 24 h) increases the expression of p-AMPK and increase in the nuclear:cytoplasmic TFEB localization[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MC2646 Related Antibodies

Western Blot Analysis[1]

Cell Line: TBL3, BL3 cells
Concentration: 4 µM
Incubation Time: 24 h
Result: Increased the LC3-II:LC3-I ratio in infected TBL3 and uninfected BL3 cells,
Molecular Weight

316.40

Formula

C21H20N2O
Unlabeled Cas

SMILES

NC1CC1C2=CC=C(C=C2)NC(CC3=CC4=CC=CC=C4C=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MC2646 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MC2646MC 2646MC-2646AutophagyParasiteTBL3 cellsautophagicp-AMPKLC3-II:LC3-ITheileria parasiteTFEBInhibitorinhibitorinhibit

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