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ML 145 

Cat. No.: HY-107536
Handling Instructions

ML 145 is a selective GPR35/CXCR8 antagonist with an IC50/EC50 of 20.1 nM, but not for the related GPR55 orphan receptor. GPR35 is expressed by various cells of the immune system and it may has potential as a therapeutic target in inflammatory disease.

For research use only. We do not sell to patients.

ML 145 Chemical Structure

ML 145 Chemical Structure

CAS No. : 1164500-72-4

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Description

ML 145 is a selective GPR35/CXCR8 antagonist with an IC50/EC50 of 20.1 nM, but not for the related GPR55 orphan receptor[1]. GPR35 is expressed by various cells of the immune system and it may has potential as a therapeutic target in inflammatory disease[2].

IC50 & Target

IC50/EC50: 20.1 nM (GPR35)[1]

Molecular Weight

482.57

Formula

C₂₄H₂₂N₂O₅S₂

CAS No.

1164500-72-4

SMILES

CC(/C=C(S1)/C(N(CCCC(NC2=CC(O)=C(C(O)=O)C=C2)=O)C1=S)=O)=C\C3=CC=CC=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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ML 145ML145ML-145OthersInhibitorinhibitorinhibit

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ML 145
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