MMV024101
MMV024101 shows potency against P. falciparum NF54 with an IC50 value of 543 nM, which has antiplasmodial activity.
For research use only. We do not sell to patients.
- CAS No.: 1092565-44-0
- Formula: C16H12N6O2S
- Molecular Weight:352.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
Chemical Information
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CAS No. 1092565-44-0
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Molecular Weight 352.37
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Formula C16H12N6O2S
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SMILES
O=S(N)(C1=CC(C2=NC3=C(C=C2)N=CC=C3C4=CNN=C4)=CN=C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
[1]. Kandepedu N, et al. Identification, Characterization, and Optimization of 2,8-Disubstituted-1,5-naphthyridines as Novel Plasmodium falciparum Phosphatidylinositol-4-kinase Inhibitors with in Vivo Efficacy in a Humanized Mouse Model of Malaria. J Med Chem. 2018 Jul 12;61(13):5692-5703. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MMV024101 Related Classifications
HY-112728 Related Classifications
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