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Cat. No.: HY-15101

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MV061194

MV061194 is a selective cathepsin K inhibitor with a human K_i of 2.5 nM. MV061194 can be used for the research of osteoporosis.

For research use only. We do not sell to patients.

CAS No.: 1021423-50-6
Formula: C₂₈H₃₇N₅O₄S
Molecular Weight:539.70

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

MV061194 Chemical Structure

CAS No.: 1021423-50-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
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Bioz

Biological Activity

Description

MV061194 is a selective cathepsin K inhibitor with a human K_i of 2.5 nM. MV061194 can be used for the research of osteoporosis^[1].

IC₅₀ & Target^[1]

cathepsin K

2.5 nM (Ki)

All Cathepsin Isoforms :

In Vitro

MV061194 potently and selectively inhibits recombinant human cathepsin K with a K_i of 2.5 nM, showing >4000-fold selectivity over multiple other cathepsin isoforms^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1021423-50-6
Molecular Weight 539.70
Formula C₂₈H₃₇N₅O₄S
SMILES

C(N[C@H]1[C@H](CC)OCC1=O)(=O)C2(NC(=O)C3=CC=C(C=C3)C=4N=C(SC4)N5CCN(C)CC5)CCCCC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Allen J G, et al. Emerging targets in osteoporosis disease modification[J]. Journal of medicinal chemistry, 2010, 53(11): 4332-4353. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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MV061194

All Cathepsin Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

MV061194 Related Classifications

HY-15101 Related Classifications