1. Epigenetics
    Protein Tyrosine Kinase/RTK
    JAK/STAT Signaling
    Stem Cell/Wnt
  2. JAK
  3. NSC 33994

NSC 33994 

Cat. No.: HY-18293
Handling Instructions

NSC 33994 (G6) is a selective JAK2 inhibitor, with an IC50 of 60 nM.

For research use only. We do not sell to patients.

NSC 33994 Chemical Structure

NSC 33994 Chemical Structure

CAS No. : 82058-16-0

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NSC 33994 (G6) is a selective JAK2 inhibitor, with an IC50 of 60 nM[1].

IC50 & Target[1]


60 nM (IC50, JAK2 Val617Phe kinase activity )

In Vitro

NSC 33994 (G6) reduces the levels of phospho-JAK2 in both a dose- and time-dependent manner[1].
NSC 33994 (G6, 0-25 μM, 0-48 h) inhibits phospho-JAK2 (pY1007/pY1008) in a dose-dependent and time-dependent manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight







Room temperature in continental US; may vary elsewhere.


Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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