NUCC-0227323
NUCC-0227323 is a TG2 PROTAC degrader. NUCC-0227323 promotes TG2 ubiquitination and degradation. NUCC-0227323 can be used for cancer research.
(Pink: TG2 ligand (HY-190616); Blue: Cereblon ligand (HY-W087383); Black: linker (HY-W184476)).
For research use only. We do not sell to patients.
- CAS No.: 3054388-12-1
- Formula: C37H38N8O6
- Molecular Weight:690.75
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
IC50 & Target
[1]|
Cereblon |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:SKOV3
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Concentration:0.1, 1, 10 μM
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Incubation Time:24 h
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Result:Showed degradation of TG2 in
SKOV3 cells.
Chemical Information
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CAS No. 3054388-12-1
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Molecular Weight 690.75
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Formula C37H38N8O6
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SMILES
CC1=CC(N(CCOCCNC2=CC3=C(C(N(C4CCC(NC4=O)=O)C3=O)=O)C=C2)C)=NC(NC5=CC=C(NC(CC6=CC=CC=C6)=O)C=C5)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NUCC-0227323 Related Classifications
HY-190650 Related Classifications
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