O-Desmethyl apremilast
O-Desmethyl apremilast is a PDE4 and TNF-α inhibitor with IC50 values of 8.3 μM and 5.6 μM, respectively. O-Desmethyl apremilast is used in inflammation, tumor, and immune-related research.
For research use only. We do not sell to patients.
- CAS No.: 1384441-38-6
- Formula: C21H22N2O7S
- Molecular Weight:446.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
PDE4 8.3 μM (IC50) |
TNF-α 5.6 μM (IC50) |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1384441-38-6
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Molecular Weight 446.47
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Formula C21H22N2O7S
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SMILES
CS(C[C@H](C1=CC(OCC)=C(C=C1)O)N2C(C3=C(NC(C)=O)C=CC=C3C2=O)=O)(=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)