Oximonam
Oximonam (SQ 82291) is a synthetic monocyclic β-lactam antibiotic with strong affinity for Gram-negative bacterial penicillin-binding protein 3 (PBP-3). Oximonam exhibits antibacterial activity against Enterobacteriaceae and Haemophilus influenzae. Oximonam can be used in research related to bacterial infections.
For research use only. We do not sell to patients.
- CAS No.: 90898-90-1
- Formula: C12H15N5O6S
- Molecular Weight:357.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
Oximonam exhibits varying degrees of antibacterial activity in agar dilution MIC testing against clinically isolated Enterobacteriaceae and H. influenzae; the MIC90 values for E. coli, Shigella spp., Citrobacter freundii, Salmonella spp., Klebsiella pneumoniae, K. oxytoca, Enterobacter spp., Serratia marcescens, Proteus mirabilis, P. vulgaris, Morganella morganii, Yersinia enterocolitica, and H. influenzae are 0.25, 0.5, 8, 0.5, 8, 1, 16, 8, 0.25, 0.5, 16, 1, and 2 mg/L, respectively[1].
Oximonam lacks effective activity against 31 strains of Staphylococcus aureus and the 232 strains of S. epidermidis described in the text, with MICs all ≥128 mg/L; Oximonam also lacks effective activity against P. aeruginosa, requiring ≥128 mg/L to inhibit the strains[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 90898-90-1
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Molecular Weight 357.34
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Formula C12H15N5O6S
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SMILES
CO/N=C(C1=CSC(N)=N1)\C(N[C@H]2[C@@H](N(C2=O)OCC(O)=O)C)=O
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Synonyms
SQ 82291
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Oximonam Related Classifications
HY-187915 Related Classifications
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