PARP1-IN-48
PARP1-IN-48 (Compound 61) is a highly selective PARP1 (PARP1 IC50 = 3 nM, PARP2 IC50 = 170 nM) inhibitor. PARP1-IN-48 can be used for research on cancer, viral infections, and metabolic conditions.
For research use only. We do not sell to patients.
- CAS No.: 3085256-81-8
- Formula: C18H24N4OS
- Molecular Weight:344.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
PARP1 |
Chemical Information
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CAS No. 3085256-81-8
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Molecular Weight 344.47
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Formula C18H24N4OS
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SMILES
CCC(N1CCN(CC1)CC2=CC3=C(N=C2)C=C(C(N3)=O)CC)=S
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)