PDE4-IN-24
Based on 1 Customer Validation
PDE4-IN-24 (compoud 14h) is a potent inhibitor of PDE4D with the IC50 of 0.57 nM and >4100-fold selectivity over other PDE families. PDE4-IN-24 plays an important role in inflammatory disease.
For research use only. We do not sell to patients.
- Purity: 99.44%
- CAS No.: 3087059-29-5
- Formula: C20H18F2N4O3S
- Molecular Weight:432.44
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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PDE4D 0.57 nM (IC50) |
Chemical Information
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CAS No. 3087059-29-5
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Appearance Solid
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Molecular Weight 432.44
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Formula C20H18F2N4O3S
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Color Light yellow to light brown
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SMILES
O=C(NCC1=NC=CC=N1)C2=CSC(C3=CC=C(C(OCC4CC4)=C3)OC(F)F)=N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 90 mg/mL (208.12 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3125 mL | 11.5623 mL | 23.1246 mL | 57.8115 mL |
| 5 mM | 0.4625 mL | 2.3125 mL | 4.6249 mL | 11.5623 mL | |
| 10 mM | 0.2312 mL | 1.1562 mL | 2.3125 mL | 5.7811 mL | |
| 15 mM | 0.1542 mL | 0.7708 mL | 1.5416 mL | 3.8541 mL | |
| 20 mM | 0.1156 mL | 0.5781 mL | 1.1562 mL | 2.8906 mL | |
| 25 mM | 0.0925 mL | 0.4625 mL | 0.9250 mL | 2.3125 mL | |
| 30 mM | 0.0771 mL | 0.3854 mL | 0.7708 mL | 1.9270 mL | |
| 40 mM | 0.0578 mL | 0.2891 mL | 0.5781 mL | 1.4453 mL | |
| 50 mM | 0.0462 mL | 0.2312 mL | 0.4625 mL | 1.1562 mL | |
| 60 mM | 0.0385 mL | 0.1927 mL | 0.3854 mL | 0.9635 mL | |
| 80 mM | 0.0289 mL | 0.1445 mL | 0.2891 mL | 0.7226 mL | |
| 100 mM | 0.0231 mL | 0.1156 mL | 0.2312 mL | 0.5781 mL |
PDE4-IN-24 Related Classifications
HY-169981 Related Classifications
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