Labeled Peptides

RAD21 (356–395), biotin labeled is biotin-labeled RAD21 (356–395) (HY-P10931). RAD21 (356–395) is a peptide encompassing amino acids 356 to 395 of the RAD21 protein, which can be used to study the interaction mechanism between STAG1 and RAD21. The equilibrium dissociation constant (K_D) value for the interaction between RAD21 (356–395) and STAG1 is 127 nM.

FITC-Tuftsin is a fluorescent probe and a Tuftsin (HY-P0240) receptor ligand that enters macrophages via receptor-mediated internalization, and its uptake is enhanced under Lipopolysaccharides, from E. coli O111:B4 (LPS) (HY-D1056A1)-stimulated macrophage activation. FITC-Tuftsin is used for the study of macrophage-mediated inflammation.

Kemptide-FITC is a fluorescently labeled Kemptide (HY-P0248). Kemptide is a synthetic heptapeptide that acts as a specific substrate for cAMP-dependent protein kinase (PKA). Kemptide-FITC enables the quantification of PKA activity and can also indirectly determine cAMP concentrations through the activation of PKA in sperm insoluble fractions. Kemptide-FITC is applicable for kinase mobility shift assay (KiMSA), and its fluorescent signal shows a linear response with increasing peptide amount within a specific range on agarose gels.

FAHF is a polypeptide-based dual-signal fluorescent colorimetric probe synthesized by conjugating the 5-carboxyfluorescein (5-FAM) (HY-66022) fluorophore to the Ala-His-Phe-NH₂ tripeptide backbone. FAHF achieves highly selective recognition of Cu²⁺ via fluorescence quenching and colorimetric change. The FAHF-Cu²⁺ complex responds to Glyphosate (HY-B0863) based on the displacement effect, resulting in fluorescence enhancement and a visually distinguishable color change. FAHF can penetrate cell membranes to enable cascade detection of copper (II) and glyphosate in living cells, and it can also be combined with smartphone RGB analysis for semi-quantitative identification.

VCAM1 binding peptide, FITC labeled acetate is a FITC-labeled VCAM1 binding peptide acetate (HY-P11088A). VCAM1 binding peptide acetate is a VCAM1 binder with internalization activity. VCAM1 binding peptide acetate serves as a component of biosensing systems for visualizing in vitro VCAM1 endocytic pathways. VCAM1 binding peptide acetate forms the research and development basis for MacroP and NAMP, PET radiotracers targeting VCAM1. VCAM1 binding peptide acetate is applicable to studies related to atherosclerosis.

Cyclo (Val-Val-Ile-d-Ala-Trp (Bodipy)-Gly) is a cyclic peptide-BODIPY conjugate. Cyclo (Val-Val-Ile-d-Ala-Trp (Bodipy)-Gly) detects prefibrillar Aβ_1-42 aggregates in neuronal cells, generating perinuclear punctate fluorescent spots. Cyclo (Val-Val-Ile-d-Ala-Trp (Bodipy)-Gly) is applicable to Alzheimer's disease-related research.

TPE-GGH is a water-soluble aggregation-induced emission (AIE)-active fluorescent probe composed of tetraphenylethylene (TPE)-modified tripeptide (Gly-Gly-His-NH₂). TPE-GGH detects Cu²⁺ with high selectivity and sensitivity, with a limit of detection of 28.5 nM. TPE-GGH exhibits low toxicity and favorable membrane permeability, and can be used for Cu²⁺ imaging in living cells (LLC) and zebrafish, as well as for Cu²⁺ detection in environmental water samples and semi-quantitative analysis via portable test strips/smartphone RGB technology.

Biotin-FRETS-VWF73 TFA is a biotin-labeled 73-amino acid peptide. FRETS-VWF73 TFA is a fluorescent substrate for ADAMTS13 detection (Ex=340 nm; Em=450 nm).

Cy5-β-Amyloid (42-1), human is a Cy5 fluorescently-labelled β-Amyloid (42-1, human) peptide (λ_ex= 633 nm and λ_em= 670 nm). β-Amyloid (42-1), human is the inactive form of Amyloid β Peptide (1-42). Its active form, β-Amyloid (1-42), may play a key role in the pathogenesis of Alzheimer's disease.

CY5-β-Amyloid (1-42), (rat/mouse) (CY5-Ahx-Amyloid β-peptide (1-42) (rat/mouse)) is a far-red fluorescent dye Cy5-labeled β-Amyloid (1-42), (rat/mouse) (HY-P1388) (Ex/Em ≈ 651 nm/670 nm). CY5-β-Amyloid (1-42), (rat/mouse) can be used in the basic research of Alzheimer's disease (AD) and related neurodegenerative diseases to monitor the aggregation, distribution and interaction of Aβ peptide segments in real time.

GIP, Cy5 labeled TFA is a Cy5-labeled gastric inhibitory polypeptide (GIP), which is specifically used to label endogenously/exogenously expressed glucose-dependent insulinotropic polypeptide receptor (GIPR).

Semaglutide, Cy5-labeled (Semaglutide-Cys(Cy5)) is a CY5 (HY-D0821) -labeled version of Semaglutide (HY-114118) (Ex/Em = 633/670 nm). Semaglutide, Cy5-labeled can be used for studies on Semaglutide receptor binding (GLP-1R), cellular uptake and endocytosis, in vivo tissue distribution, and the targeting efficiency of delivery systems.

Biotin-CRF, human, rat is a biotin-conjugated CRF (human, rat). CRF (human, rat) is a corticotropin-releasing hormone, paraventricular hypothalamic nucleus marker.

(Z-AR)2Rh110 is a Rhodamine derivative. (Z-AR)2Rh110 can be hydrolyzed by trypsin.

Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton.

Cy5-TAT acetate is a TAT peptide labeled with CY5 (HY-D0821) (Ex= 600-620 nm, Em= 670 nm). Cy5-TAT acetate can be used for fluorescence microscopy especially single-molecule fluorescence imaging.

Cronexitide lanocianine is a diagnostic imaging agent.

Biotinylated CCDC61 peptide (CAPture peptide, biotin-CCDC61 (334-366)) is a biotinylated peptide derived from the centrosomal protein CCDC61. Biotinylated CCDC61 peptide specifically isolates intact centrosomes.

QMT-CBT is a near-infrared aggregation-induced luminescent photon. After activation of caspase1 (Cas1), QMT-CBT undergoes a CBT-Cys click reaction to form a cyclic dimer QMT-Dimer (the first aggregate) and assembles into nanoparticles (the second aggregate), turning the AIE signal "on" to enhance imaging of Alzheimer's disease (AD).