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Cat. No.: HY-160283

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PI3K-IN-50

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

PI3K-IN-50 is a phosphotidylinositol-3-kinase (PI3K) inhibitor extracted from patent WO2023239710A1, example 35.

For research use only. We do not sell to patients.

CAS No.: 3023536-43-5
Formula: C₂₄H₂₅F₄N₅O₃
Molecular Weight:507.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

PI3K-IN-50 Chemical Structure

CAS No.: 3023536-43-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

PI3K-IN-50 is a phosphotidylinositol-3-kinase (PI3K) inhibitor extracted from patent WO2023239710A1, example 35^[1].

All PI3K Isoforms :

Chemical Information

CAS No. 3023536-43-5
Molecular Weight 507.48
Formula C₂₄H₂₅F₄N₅O₃
SMILES

OC(C(C=CC=C1)=C1N[C@@H](C2=C3C(C(N(C(N4CCN(CC4)CC(F)(F)F)=N3)C)=O)=CC(F)=C2)C)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Cell Death Discov

Combination of HDAC inhibitor and PI3K inhibitor suppresses autophagy and induces apoptosis via cytoplasmic IκBα stabilization in p53-mutant diffuse large B-cell lymphoma. [Abstract]

2025 Oct 6;11(1):445. PMID: 41053160

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Blake JF, et al. Benzopyrimidin-4(3h)-ones as pi3k inhibitors. France, WO2023239710A1. 2023-12-14.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Chemical Information
Publications (1)
Purity & Documentation
References

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PI3K-IN-50

Publications Citing Use of MedChemExpress (MCE) PI3K-IN-50

All PI3K Isoforms