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Cat. No.: HY-163361

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PI3Kα-IN-20

PI3Kα-IN-20 (compound 2) is a selective PI3Kα inhibitor.

For research use only. We do not sell to patients.

CAS No.: 228999-57-3
Formula: C₂₂H₂₄N₄O₄
Molecular Weight:408.45

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

PI3Kα-IN-20 Chemical Structure

CAS No.: 228999-57-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

PI3Kα-IN-20 (compound 2) is a selective PI3Kα inhibitor^[1].

IC₅₀ & Target^[1]

PI3Kα

All PI3K Isoforms :

Chemical Information

CAS No. 228999-57-3
Molecular Weight 408.45
Formula C₂₂H₂₄N₄O₄
SMILES

CNC(C1=CC=C(C=C1)OC2=CC=C(C=C2)NC(NC3=NOC(C(C)(C)C)=C3)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Shafiq M, et al. A deep learning-based theoretical protocol to identify potentially isoform-selective PI3Kα inhibitors. Mol Divers. 2024 Feb 2. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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