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Cat. No.: HY-139880

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PI3Kγ inhibitor 5

PI3Kγ inhibitor 5 is an inhibitor of phosphoinositide 3-kinase γ (PI3Kγ) with an IC₅₀ value of 34 nM.

For research use only. We do not sell to patients.

CAS No.: 2566569-31-9
Formula: C₂₈H₃₂F₂N₆O₄
Molecular Weight:554.59

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

PI3Kγ inhibitor 5 Chemical Structure

CAS No.: 2566569-31-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

PI3Kγ inhibitor 5 is an inhibitor of phosphoinositide 3-kinase γ (PI3Kγ) with an IC₅₀ value of 34 nM.

All PI3K Isoforms :

Chemical Information

CAS No. 2566569-31-9
Molecular Weight 554.59
Formula C₂₈H₃₂F₂N₆O₄
SMILES

O=C(C1=C2N=C(C3=CC4=C(C(N([C@H](C5CC5)C)C4)=O)C(OC(F)F)=C3)C=CN2N=C1N)N[C@H]6CC[C@@](C)(O)CC6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mata G, et al. Design, Synthesis, and Structure-Activity Relationship Optimization of Pyrazolopyrimidine Amide Inhibitors of Phosphoinositide 3-Kinase γ (PI3Kγ). J Med Chem. 2021 Oct 21. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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