1. Epigenetics TGF-beta/Smad
  2. PKC
  3. PKCiota-IN-1

PKCiota-IN-1 (compound 51) is a potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.7 nM. PKCiota-IN-1 also inhibits PKC-α and PKC-ε with IC50s of 45 nM and 450 nM, respectively.

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PKCiota-IN-1 Chemical Structure

PKCiota-IN-1 Chemical Structure

CAS No. : 2230052-97-6

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Description

PKCiota-IN-1 (compound 51) is a potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.7 nM. PKCiota-IN-1 also inhibits PKC-α and PKC-ε with IC50s of 45 nM and 450 nM, respectively[1].

IC50 & Target[1]

PKCι

2.7 nM (IC50)

PKCα

45 nM (IC50)

PKCε

450 nM (IC50)

Molecular Weight

427.47

Formula

C25H22FN5O

CAS No.
Unlabeled CAS

SMILES

COC1=CC2=C(CNC(CF)C2)C=C1C3=C4C=C(C5=C6C(NC=C6)=NC=C5)C=CN4N=C3

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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PKCiota-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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PKCiota-IN-1
Cat. No.:
HY-122857
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