PRMT5-IN-55
PRMT5-IN-55 is an inhibitor of PRMT5 with a pIC50 value of 9.6 at a 10 nM enzyme.
For research use only. We do not sell to patients.
- CAS No.: 2086772-19-0
- Formula: C22H24N6O2
- Molecular Weight:404.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Histone Methyltransferase Isoforms
More
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
0.16 nM
Compound: 19
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Inhibition of PRMT5 in human A549 cells assessed as reduction in sDMA production after 48 hrs by Hoechst Stain/HCS CellMask Deep Red Stain based immunohistochemistry method
Inhibition of PRMT5 in human A549 cells assessed as reduction in sDMA production after 48 hrs by Hoechst Stain/HCS CellMask Deep Red Stain based immunohistochemistry method
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[PMID: 30956011] |
Chemical Information
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CAS No. 2086772-19-0
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Molecular Weight 404.46
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Formula C22H24N6O2
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SMILES
NC1=NC2=CC(CC[C@H]3C[C@H]([C@@H]([C@@H]3O)O)N4C=CC5=C4N=CN=C5N)=CC=C2C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PRMT5-IN-55 Related Classifications
HY-181294 Related Classifications
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