PROTAC Cdc25 degrader-1
PROTAC Cdc25 degrader-1 (Compound D3) is an efficient Cdc25 PROTAC degrader. Its DC50 values for Cdc25A, Cdc25B, and Cdc25C are 0.97, 2.02, and 4.67 μM respectively. PROTAC Cdc25 degrader-1 induces cell cycle arrest and apoptosis in cancer cells and inhibits cell migration ability. PROTAC Cdc25 degrader-1 significantly increases the ROS level. PROTAC Cdc25 degrader-1 can be used for the study of colorectal adenocarcinoma.
(Pink: Cdc25 Target protein ligand; Blue: VHL ligand (HY-112078); Black: linker).
For research use only. We do not sell to patients.
- Formula: C37H43ClN6O6S
- Molecular Weight:735.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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VHL |
Chemical Information
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Molecular Weight 735.29
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Formula C37H43ClN6O6S
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SMILES
O[C@@H]1C[C@H](N(C1)C([C@H](C(C)(C)C)NC(CCCCNC(C2=O)=C(C(C3=C2C=CC=N3)=O)Cl)=O)=O)C(N[C@H](C4=CC=C(C=C4)C5=C(N=CS5)C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC Cdc25 degrader-1 Related Classifications
HY-181011 Related Classifications
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